I watched a very interesting series on Netflix called The Polar Sea, and the website is http://polarsea360.arte.tv/. European adventurers sail several yachts through the Northwest Passage. They stop along the way, primarily in Inuit native villages.
We learn that, due to global warming, the traditional game such as seals are disappearing, and the Inuit are cautiously welcoming tourists, all kinds of ships, and possibly settlers. The flatlands, recently covered by glaciers, are turning into grassy areas. These may evolve to tree-covered areas where pioneers could settle.
Of course, the composition of wildlife on land and in the sea will be different than today, but this may be the last frontier as the western world dies off.
By the way: Find the open boat with some people in it in the photo.
Larry Kilham is a Sloan School of Management graduate from MIT, received three patents, and has founded two high-tech companies. Many of his product designs required innovative use of computers, and as early as the 1960s he was researching artificial intelligence (AI).